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Alkaloids from Piper sarmentosum and Piper nigrum.

Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids. The roots of P. sarmentosum gave a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1). Piper nigrum roots gave pellitorine (2), (E)-1-[3',4'-(methylenedioxy)cinnamoyl]piperidine (3), 2,4-tetradecadienoic acid isobutyl amide (4), piperine (5), sylvamide (6), cepharadione A (7), piperolactam D (8) and paprazine (9). Structural elucidation of these compounds was achieved through NMR and MS techniques. Cytotoxic activity screening of the plant extracts indicated some activity.[1]

References

  1. Alkaloids from Piper sarmentosum and Piper nigrum. Ee, G.C., Lim, C.M., Lim, C.K., Rahmani, M., Shaari, K., Bong, C.F. Nat. Prod. Res. (2009) [Pubmed]
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