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Heil, J. et al.

Genotoxicity of the fungicide dichlofluanid in seven assays.

Seven different endpoints for detection of genotoxicity have been used to demonstrate the DNA-altering properties of Dichlofluanid, a fungicide commonly used in viticulture pest control. Each endpoint (DNA synthesis inhibition test, alkaline viscosimetry, umu-test, alkaline filter elution, FADU-test, 32P-postlabeling, and electron microscopy) shows clear evidence of genotoxicity. These data indicate that application of the fungicide dichlofluanid may be mutagenic and/or carcinogenic for exposed humans.[1]

References

Genotoxicity of the fungicide dichlofluanid in seven assays. Heil, J., Reifferscheid, G., Hellmich, D., Hergenröder, M., Zahn, R.K. Environ. Mol. Mutagen. (1991) [Pubmed]

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