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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Pharmacokinetics of eltoprazine in healthy subjects.

The pharmacokinetics of eltoprazine in healthy male subjects was investigated after intravenous and oral dosing in one study, and after oral dosing of 14C-eltoprazine in a second study. It was shown that the absorption of eltoprazine from the gastro-intestinal tract was complete, and that absolute bioavailability was 100%. The mean elimination half-life of eltoprazine in plasma was about 8 hours. Approximately 40% of the dose was excreted unchanged in urine.[1]


  1. Pharmacokinetics of eltoprazine in healthy subjects. van Harten, J., Mathlener, I.S., Raghoebar, M. Drug metabolism and drug interactions. (1990) [Pubmed]
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