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Tietze, L.F. et al.

Lutz F. Tietze, Frank Behrendt, Galina F. Pestel, Ingrid Schuberth, Mišo Mitkovski, Frank Behrendt, Galina F. Pestel, Ingrid Schuberth, Mišo Mitkovski,

Synthesis, biological evaluation, and live cell imaging of novel fluorescent duocarmycin analogs.

For a better understanding of the mode of action of duocarmycin and its analogs, the novel fluorescent duocarmycin derivatives 13-15 and 17b-19b were synthesized, and their bioactivity as well as their cellular uptake investigated using confocal laser scanning microscopy (CLSM) in live-cell imaging experiments.[1]

References

Synthesis, biological evaluation, and live cell imaging of novel fluorescent duocarmycin analogs. Tietze, L.F., Behrendt, F., Pestel, G.F., Schuberth, I., Mitkovski, M. Chem. Biodivers. (2012) [Pubmed]

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