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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Acute laryngeal dystonic reactions to neuroleptics.

Two cases of acute laryngeal dystonia (laryngospasm), a rarely reported extrapyramidal reaction to neuroleptics, occurred in a public psychiatric hospital. A review of the literature revealed only seven well-documented case reports. This article discusses the clinical significance of this rare, alarming, and probably underreported phenomenon. Factors related to recognition, prediction, and management are also discussed. The review strongly advocates immediate intravenous administration of anticholinergic drugs to relieve dystonia.[1]


  1. Acute laryngeal dystonic reactions to neuroleptics. Koek, R.J., Pi, E.H. Psychosomatics. (1989) [Pubmed]
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