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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Pipothiazine palmitate in the management of aggressive mentally handicapped patients.

The efficacy of intramuscular pipothiazine palmitate (PP) in the management of aggressive mentally handicapped patients was examined in a double-blind, placebo-controlled, cross-over study, in which 30 patients received each treatment for 13 weeks. A target symptom scale of aggressiveness (TSA) and a clinical global impression scale of efficacy were rated at monthly intervals, and an extra-pyramidal side-effects scale weekly. The patients showed marked improvement during treatment with PP, which was assessed as superior to placebo. Individual and total TSA scores were also reduced compared to placebo.[1]

References

  1. Pipothiazine palmitate in the management of aggressive mentally handicapped patients. Lynch, D.M., Eliatamby, C.L., Anderson, A.A. The British journal of psychiatry : the journal of mental science. (1985) [Pubmed]
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