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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Impact of virus infection on host cell protein synthesis.

There is good evidence that a variety of viruses encode functions that inhibit activation of either ribonuclease L or the Pl/eIF-2 alpha kinase. In general, this capability is evident among viruses that maintain long-term active or latent infections, and must therefore deal with interferon-induced antiviral responses of their hosts.[1]


  1. Impact of virus infection on host cell protein synthesis. Schneider, R.J., Shenk, T. Annu. Rev. Biochem. (1987) [Pubmed]
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