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Ramsay, M. et al.

Mutations for the autosomal recessive and autosomal dominant forms of polycystic kidney disease are not allelic.

The autosomal dominant form of polycystic kidney disease (ADPKD) has been linked to the alpha-globin gene locus on 16p. Linkage studies between the autosomal recessive type (ARPKD) and the 3' HVR of the alpha-globin gene cluster showed that the ARPKD and ADPKD are not allelic.[1]

References

Mutations for the autosomal recessive and autosomal dominant forms of polycystic kidney disease are not allelic. Ramsay, M., Reeders, S.T., Thomson, P.D., Milner, L.S., Lazarou, L., Barratt, T.M., Yau, A., Lehmann, O.J., Jenkins, T. Hum. Genet. (1988) [Pubmed]

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