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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

One factor recognizes the liver-specific enhancers in alpha 1-antitrypsin and transthyretin genes.

Four different regulatory sites required for transcriptional stimulation by the enhancers of two unrelated liver-specific genes alpha 1-antitrypsin and transthyretin appear to bind the same nuclear protein that is found mainly in the liver. Such proteins may provide a basis for a coordinated, hepatocyte-specific control of gene transcription.[1]

References

  1. One factor recognizes the liver-specific enhancers in alpha 1-antitrypsin and transthyretin genes. Grayson, D.R., Costa, R.H., Xanthopoulos, K.G., Darnell, J.E. Science (1988) [Pubmed]
 
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