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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effects of 4-acetylpyridine on stress ulcer formation in mice.

4-Acetylpyridine, earlier reported by us to be an anticonvulsant, offers long-lasting protection after a single administration against hypothermic restraint stress-induced gastric ulceration in mice. Electroshock convulsions, marginally but not significantly protective against such ulcers themselves, when coupled with 4-acetylpyridine administration fully prevented gastric ulcers from occurring in this murine model of experimentally induced stress.[1]


  1. Effects of 4-acetylpyridine on stress ulcer formation in mice. Hall, A., Bose, R., Glavin, G., Pinsky, C. Neurosci. Lett. (1988) [Pubmed]
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