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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Quantitative confirmation of dimetridazole and ipronidazole in swine feed by capillary gas chromatography/ mass spectrometry with multiple ion detection.

Extracts from 4 types of swine feed containing 0.11 ppm each of dimetridazole (DMZ) and ipronidazole (IPR) were analyzed by capillary gas chromatography/ mass spectrometry (GC/MS) using multiple ion detection (MID) techniques. We demonstrate in this paper that the quantitative results obtained by capillary GC/MS with MID are comparable for both compounds to results obtained by liquid chromatography and have a lower coefficient of variation for DMZ. Moreover, consistency in the ion ratios (5 ions in DMZ and 6 ions in IPR) permits identification of these compounds by electron ionization MS.[1]

References

  1. Quantitative confirmation of dimetridazole and ipronidazole in swine feed by capillary gas chromatography/mass spectrometry with multiple ion detection. Morris, W.J., Nandrea, G.J., Roybal, J.E., Munns, R.K., Shimoda, W., Skinner, H.R. Journal - Association of Official Analytical Chemists. (1987) [Pubmed]
 
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