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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Botulinum toxin for benign essential blepharospasm, hemifacial spasm and age-related lower eyelid entropion.

Purified botulinum A exotoxin was used in the treatment of forty seven patients with benign essential blepharospasm, 11 patients with hemifacial spasm and 2 patients with age-related entropion. The treatment was effective in all three groups for an average of 3-4 months when symptoms recurred and repeated chemodenervation with toxin was needed. The commonest complication was transient ptosis with an overall frequency of 7.8%. This incidence increased to 11.1% with toxin doses higher than 25 units per orbicularis. The treatment was well accepted by the patients, who were subsequently able to return to pre-blepharospasm lifestyles.[1]

References

  1. Botulinum toxin for benign essential blepharospasm, hemifacial spasm and age-related lower eyelid entropion. Carruthers, J., Stubbs, H.A. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (1987) [Pubmed]
 
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