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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sotos syndrome--autosomal dominant inheritance substantiated.

Sotos syndrome, or Cerebral Gigantism is recognised as the syndromic association of mental retardation, macrocephaly and prenatal onset of accelerated growth. A kindred has been investigated in which the father and 4 affected offspring all have the Sotos syndrome. Autosomal dominant inheritance has been postulated in the past, and the family conform to this genetic pattern.[1]


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