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Shashindran, C. et al.

Anticonvulsant action of thiabendazole.

Thiabendazole was found to be specifically effective against maximal electroshock seizures in albino rats. It produced a significant dose-dependent decrease in the duration of the tonic extensor phase of hind legs. The ED50 was similar for oral or s.c. administration. PTZ-induced convulsions were unaffected by lower doses but aggravated by the higher dose studied.[1]

References

Anticonvulsant action of thiabendazole. Shashindran, C., Gandhi, I.S., Parmar, N.S. Eur. J. Pharmacol. (1977) [Pubmed]

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