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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Anticonvulsant action of thiabendazole.

Thiabendazole was found to be specifically effective against maximal electroshock seizures in albino rats. It produced a significant dose-dependent decrease in the duration of the tonic extensor phase of hind legs. The ED50 was similar for oral or s.c. administration. PTZ-induced convulsions were unaffected by lower doses but aggravated by the higher dose studied.[1]


  1. Anticonvulsant action of thiabendazole. Shashindran, C., Gandhi, I.S., Parmar, N.S. Eur. J. Pharmacol. (1977) [Pubmed]
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