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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Study of the target cell of the dengue virus-induced suppressor signal.

Dengue type 2 virus (DV) induces two generations of T suppressor cells (Ts1 and Ts2) in murine spleen. The Ts2 cells produce a soluble factor ( SF2 ) which suppresses DV-specific IgM antibody plaque-forming cells (PFC). In this study the target cell of SF2 was examined. The results show that SF2 requires a third generation of T cells (T3) in order to mediate suppression. The surface phenotype of this T3 cell is Ly 1+ and the suppression mediated is antigen specific.[1]

References

  1. Study of the target cell of the dengue virus-induced suppressor signal. Shukla, M.I., Chaturvedi, U.C. British journal of experimental pathology. (1984) [Pubmed]
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