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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Catecholamine-induced alteration in sedimentation behavior of membrane bound beta-adrenergic receptors.

Incubation of astrocytoma cells with catecholamines results in a decrease in catecholamine-stimulated adenylate cyclase activity and a concomitant alteration in the sedimentation properties of particulate beta-adrenergic receptors. The altered receptors exhibit agonist binding properties similar to those of receptors that are "uncoupled" from adenylate cyclase.[1]

References

  1. Catecholamine-induced alteration in sedimentation behavior of membrane bound beta-adrenergic receptors. Harden, T.K., Cotton, C.U., Waldo, G.L., Lutton, J.K., Perkins, J.P. Science (1980) [Pubmed]
 
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