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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Effect of CO2-induced hyperventilation on carbon tetrachloride (CCl4) levels following acute CCl4 poisoning.

To study under standardized experimental conditions the effect of a CO2-induced hyperventilation therapy on carbon tetrachloride (CCl4) levels following acute CCl4 poisoning, rats received 2.5 ml CCl4/kg BW by gastric intubation and were subsequently either treated by CO2-induced hyperventilation or kept in an atmosphere containing air. Peak levels of CCl4 were observed in the fat, liver and blood 3-6 h after the intoxication and were found to be considerably lower in animals treated by CO2-induced hyperventilation compared to their respective controls. These data therefore strongly support the efficacy of the CO2-induced hyperventilation therapy for CCl4 intoxication.[1]

References

  1. Effect of CO2-induced hyperventilation on carbon tetrachloride (CCl4) levels following acute CCl4 poisoning. Gellert, J., Goldermann, L., Teschke, R. Intensive care medicine. (1983) [Pubmed]
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