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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Zomepirac sodium (Zomax) hypersensitivity in aspirin-sensitive asthmatics.

Three asthmatic patients with a history of bronchoconstriction after aspirin ingestion were challenged with a new analgesic, zomepirac sodium (Zomax), for determination of sensitivity to this drug. Each patient had previously demonstrated sensitivity to aspirin during oral provocative challenges. In all 3 patients, zomepirac produced the typical asthmatic and nasal response, indicating hypersensitivity. These findings indicate that zomepirac sodium is not tolerated in aspirin-sensitive asthmatics and should not be prescribed to such patients.[1]

References

  1. Zomepirac sodium (Zomax) hypersensitivity in aspirin-sensitive asthmatics. Pleskow, W.W., Lumry, W.R., Simon, R.A. Am. Rev. Respir. Dis. (1984) [Pubmed]
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