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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Porokeratosis (Mibelli): treatment with topical 5-fluorouracil.

The case history of a patient with a solitary classic porokeratosis (Mibelli) on the hand is described. The lesion cleared without scarring with the use of topical 5-fluorouracil until a strong dermatitis was elicited, thus avoiding surgery and attendant restriction of function. No sign of recurrence developed in the following 2 years. The potential for malignant change in porokeratosis (Mibelli) and its resistance to topical treatment as documented in the literature are also reviewed.[1]

References

  1. Porokeratosis (Mibelli): treatment with topical 5-fluorouracil. McDonald, S.G., Peterka, E.S. J. Am. Acad. Dermatol. (1983) [Pubmed]
 
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