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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Dexamethasone, aldosterone and kallikrein release by isolated rat kidney.

1. The effect of D-aldosterone and dexamethasone on kallikrein release was studied in the isolated rat kidney perfused with modified Krebs-Henseleit buffer. 2. Animals received D-aldosterone or dexamethasone (10 microgram/100 g body weight) daily for 3 days. Their isolated kidneys were then perfused with the same steroids at rates of 2.0-2.5 microgram/min for 30 min. 3. Dexamethasone increased kallikrein release significantly (P less than 0.001) both in urine and in venous outflow. 4. D-Aldosterone had no significant effect on kallikrein release, either in urine or in venous outflow.[1]

References

  1. Dexamethasone, aldosterone and kallikrein release by isolated rat kidney. Vio, C.P., Roblero, J.S., Croxatto, H.R. Clin. Sci. (1981) [Pubmed]
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