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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Aortocoronary bypass procedures and sternotomy infections: a study of antistaphylococcal prophylaxis.

In a prospective study of cephalothin prophylaxis for patients who underwent aortocoronary bypass an unacceptably high rate (44%) of Staphylococcus aureus sternotomy infections occurred in a placebo-treated group. In two other groups of patients, one group given cephalothin intraoperatively and the other given the antibiotic both intra- and postoperatively, such infections occurred with similar frequency (2.6% and 2.1% respectively). This study demonstrates the need for antistaphylococcal agents during aortocoronary bypass operation. No advantage is derived by extending this therapy beyond the operative period.[1]

References

  1. Aortocoronary bypass procedures and sternotomy infections: a study of antistaphylococcal prophylaxis. Austin, T.W., Coles, J.C., Burnett, R., Goldbach, M. Canadian journal of surgery. Journal canadien de chirurgie. (1980) [Pubmed]
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