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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Kidney transport of cefapirin in normal and impaired renal function.

The renal transport of cefapirin has been assessed in thirteen patients after one dose of 1.0 g i.m. In normal glomerular filtration rate, approximately 50-60% of the dose is recovered in the urine in active form. The corresponding figure in functions below 30 ml/min was 10-30%. In normal function, tubular secretion accounts for ca. 1/4-1/3 of the amount appearing in the urine.[1]

References

  1. Kidney transport of cefapirin in normal and impaired renal function. Brodwall, E.K., Orjavik, O., Bergan, T. Arzneimittel-Forschung. (1981) [Pubmed]
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