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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Inhibition of two homeotic mutants of Drosophila by 5-bromodeoxyuridine and fluorouracil.

Nasobemia (Ns) and spineless-aristapedia (ssa40a) are dominant and recessive homeotic mutants of Drosophila which convert parts of the antenna to leg structures. Exposure of Ns and ssa40a larvae to half-lethal concentrations of 5-bromodeoxyuridine (BUdR) and flourouracil (FU) together or separately during the presumptive time of gene action suppresses the expressivity and penetrance of the mutants.[1]

References

  1. Inhibition of two homeotic mutants of Drosophila by 5-bromodeoxyuridine and fluorouracil. Ibars, G.C., Selick, H.E., Kauffman, S.A. J. Exp. Zool. (1981) [Pubmed]
 
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