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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Malyngamide H, an ichthyotoxic amide possessing a new carbon skeleton from the Caribbean cyanobacterium Lyngbya majuscula.

Guided by ichthyotoxic activity against goldfish, a new lipopeptide, malyngamide H ¿1¿, and its corresponding free acid, 7-methoxytetradec-4(E)-enoic acid ¿2¿, have been isolated from the tropical marine cyanobacterium Lyngbya majuscula. The structure of the new carbon skeleton borne by malyngamide H was elucidated on the basis of spectroscopic analysis, mainly 2D nmr. The absolute stereochemistry of the cyclohexenone moiety of malyngamide H -1- was deduced by a combination of 2D NOESY and exciton chirality circular dichroism spectroscopy.[1]

References

  1. Malyngamide H, an ichthyotoxic amide possessing a new carbon skeleton from the Caribbean cyanobacterium Lyngbya majuscula. Orjala, J., Nagle, D., Gerwick, W.H. J. Nat. Prod. (1995) [Pubmed]
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