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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Electroencephalographic findings in patients with mild Parkinson's disease treated with L-dopa and placebo.

The prognostic value of electroencephalograms in patients with early or mild Parkinson's disease treated with L-dopa is discussed. Fifteen patients with early or mild Parkinson's disease were studied clinically and electroencephalographically while receiving L-dopa or placebo treatment. Only a low incidence (four patients, 27%) of EEG abnormality was found. These patients showed only mild improvement: in three cases, the improvement followed an initial worsening in the first three months. Only one (13%) of the patients with a normal EEG became worse or failed to improve. The potential use of EED data in parkinsonism is discussed.[1]


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