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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23.

The human OTF1 locus encoding the Oct-1 protein has previously been mapped to chromosome 1 cen-->q32 by analysis of somatic cell hybrids. We report here the regional localization of OTF1 to 1q22-->q23 by fluorescence in situ hybridization. The physical linkage of the CD3Z gene to the OTF1 transcription unit also refines the location of the CD3Z locus to 1q22-->q23.[1]


  1. The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23. Sturm, R.A., Eyre, H.J., Baker, E., Sutherland, G.R. Cytogenet. Cell Genet. (1995) [Pubmed]
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