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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sphenoid wing meningioma progression after placement of a subcutaneous progesterone agonist contraceptive implant.

A causal relationship between sex steroids and meningioma proliferation has long been suspected. We report a case of the clinical progression of a sphenoid wing meningioma after the placement of Norplant, a subcutaneous contraceptive implant containing levonorgestrel, a progesterone agonist. Although not proof of causation, this observation lends further credence to the importance of progesterone receptors in the growth and possible treatment of meningiomas.[1]


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