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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The "pseudo-CSF" signal of orbital optic glioma on magnetic resonance imaging: a signature of neurofibromatosis.

A five-and-a-half-year-old boy with neurofibromatosis had bilateral orbital optic gliomas visible on magnetic resonance imaging. Both tumors displayed a double-intensity signal characterized by a circumferential area of CSF-intensity tissue surrounding and sharply delimited from a central linear core of opposite signal intensity. The peripheral CSF-intensity signal in orbital optic glioma correlates with the histopathological finding of perineural arachnoidal gliomatosis and serves as a neuroradiologic marker for neurofibromatosis.[1]


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