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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Synthesis and antibacterial activity of substituted 4-arylaminopyrimido[5,4-c]cinnolines.

A series of 4-arylamino pyrimido[5,4-c]cinnolines was synthesized and evaluated for antibacterial activity by serial 2-fold dilution technique. Several compounds showed significant activity. Amongst them 7-methyl-4-[(p-methyl phenyl) amino] pyrimido [5,4-c] cinnoline (2f) was the most active against Gram positive bacteria.[1]


  1. Synthesis and antibacterial activity of substituted 4-arylaminopyrimido[5,4-c]cinnolines. Nargund, L.V., Nargund, K.S. Arzneimittel-Forschung. (1995) [Pubmed]
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