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Skin side-effects of amiodarone therapy.

Amiodarone is a antiarrhythmic drug with many side-effects which include also the induction of photosensitivity and the development of greyish-blue pigmentations on the skin exposed to light. The authors examined 64 patients treated with amiodarone and 32 controls by means of a phototest using a xenon lamp. In 9.4% photosensitivity was recorded, in 9.4% there were greyish-blue hyperpigmentations in the face and on the back of the hands. Histological identification of these hyperpigmentations including electron microscopy was also performed.[1]

References

  1. Skin side-effects of amiodarone therapy. Ettler, K., Gregor, J., Pidrman, V., Subrtová, D., Nozi cková, M. Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové. (1993) [Pubmed]
 
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