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Treloar, A.J. et al.

Pupillary response to topical tropicamide as a marker for Alzheimer's disease.

The mydriatic response to eyedrops of the anticholinergic drug tropicamide at very low concentration (0.01%) was studied in subjects with Alzheimer's disease (AD, n = 10) and multi-infarct dementia (MID, n = 10). There was no significant difference in pupillary response between the two groups. The test is unlikely to be useful in differentiating different types of dementia.[1]

References

Pupillary response to topical tropicamide as a marker for Alzheimer's disease. Treloar, A.J., Assin, M., Macdonald, A.J. British journal of clinical pharmacology. (1996) [Pubmed]

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