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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Risperidone-induced neuroleptic malignant syndrome: a case report and review.

OBJECTIVES: 1. To report the case of a 53-year-old patient who developed neuroleptic malignant syndrome (NMS) - a rare but potentially life-threatening complication of neuroleptic therapy - 4 days after treatment with risperidone was initiated. 2. To review previously reported cases of NMS associated with risperidone. METHODS: A computerized search of several databases, including MEDLINE, was conducted to find all previously reported cases of NMS with risperidone. RESULTS: Five reported cases of risperidone-induced NMS were found in the literature. All cases including the one reported here displayed typical clinical features of NMS and all 6 patients had a prior history of extrapyramidal side effects and/or NMS. Age and duration of exposure to risperidone did not seem to be of significance. CONCLUSIONS: These cases illustrate that clinicians should be on the lookout for risperidone-induced NMS.[1]

References

  1. Risperidone-induced neuroleptic malignant syndrome: a case report and review. Meterissian, G.B. Canadian journal of psychiatry. Revue canadienne de psychiatrie. (1996) [Pubmed]
 
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