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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human.

We report here on the identification and genomic mapping of a novel member of the family of the ATP-binding cassette ( ABC) transporters, ABC7, conserved in mouse and in humans. The ABC7 gene encodes a protein with the typical features of half-transporters, such as those involved in translocation of antigenic peptides or in peroxisomal disorders. ABC7 shows a ubiquitous expression pattern and maps to the X chromosome both in mouse and in humans. The high sequence similarity to those of two yeast half-transporters supports once again the extreme evolutionary conservation of this family of proteins.[1]

References

  1. Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human. Savary, S., Allikmets, R., Denizot, F., Luciani, M.F., Mattei, M.G., Dean, M., Chimini, G. Genomics (1997) [Pubmed]
 
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