- Randomized, double-blind comparison of hirulog versus heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO). Hirulog Early Reperfusion/Occlusion (HERO) Trial Investigators. White, H.D., Aylward, P.E., Frey, M.J., Adgey, A.A., Nair, R., Hillis, W.S., Shalev, Y., Brown, M.A., French, J.K., Collins, R., Maraganore, J., Adelman, B. Circulation (1997)