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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Isolations of a cartilage factor that inhibits tumor neovascularization.

A cartilage fraction isolated by guanidine extraction and purified by affinity chromatography inhibits tumor-induced vascular proliferation and consequently restricts tumor growth. This fraction contains several different proteins; the major one has a molecular weight of about 16,000. The fraction strongly inhibits protease activity.[1]

References

  1. Isolations of a cartilage factor that inhibits tumor neovascularization. Langer, R., Brem, H., Falterman, K., Klein, M., Folkman, J. Science (1976) [Pubmed]
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