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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Critical tests of anthelmintic activity of a paste formulation of thiabendazole in horses.

Critical tests of the activity on large strongyles, ascarids, mature pinworms, and bots were carried out in 11 horses intraorally treated with a paste formulation of thiabendazole. The dose level of 44 mg/kg was administered to 3 horses, and the dose level of 88 mg/kg to 8 horses. Removals of Strongylus vulgaris and mature Oxyuris equi were 100% at the 2 dose levels, and efficacy against Strongylus edentatus varied from 95 to 99% and 89 to 100% for the 44- and the 88-mg/kg dose levels, respectively. Strongylus equinus was completely removed from the 1 infected horse treated at the dose level of 88 mg/kg. Activity of the smaller dose against Parascaris equorum was 46%, and that of the larger dose varied from 32 to 100%. The drug was inactive on Gasterophilus intestinalis and Gasterophilus nasalis.[1]

References

  1. Critical tests of anthelmintic activity of a paste formulation of thiabendazole in horses. Lyons, E.T., Drudge, J.H., Tolliver, S.C. Am. J. Vet. Res. (1976) [Pubmed]
 
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