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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Genomic organization and mapping of the human activin receptor type IIB (hActR-IIB) gene.

Activins, members of a family of proteins that includes transforming growth factor-beta (TGF-beta), are gonadal polypeptide hormones that stimulate secretion of follicle-stimulating hormone (FSH). During large-scale sequencing analysis of a 1.2-Mb fragment of human genomic DNA on 3p22-p21.3, we found the gene encoding activin receptor type IIB (hActR-IIB). Comparison of its reported cDNA sequence with this genomic sequence showed that the hActR-IIB gene consists of 11 exons and spans about 30 kb of genomic DNA.[1]

References

  1. Genomic organization and mapping of the human activin receptor type IIB (hActR-IIB) gene. Ishikawa, S., Kai, M., Murata, Y., Tamari, M., Daigo, Y., Murano, T., Ogawa, M., Nakamura, Y. J. Hum. Genet. (1998) [Pubmed]
 
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