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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Enzyme replacement therapy decreases hypergammaglobulinemia in Gaucher's disease.

We report the effects of enzyme replacement therapy in a patient with Gaucher's disease associated with a monoclonal gammopathy. Alglucerase induces a linear decline in immunoglobulin and beta 2-microglobulin levels. This observation suggests that this treatment decreases the chronic antigenic stimulation commonly found in Gaucher's disease.[1]

References

  1. Enzyme replacement therapy decreases hypergammaglobulinemia in Gaucher's disease. Deibener, J., Kaminsky, P., Jacob, C., Dousset, B., Klein, M., Duc, M. Haematologica (1998) [Pubmed]
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