Gene Review:
NPFFR2 - neuropeptide FF receptor 2
Homo sapiens
Synonyms:
G-protein coupled receptor 74, G-protein coupled receptor HLWAR77, GPR74, HLWAR77, NPFF2, ...
- Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus. Laemmle, B., Schindler, M., Beilmann, M., Hamilton, B.S., Doods, H.N., Wieland, H.A. Regul. Pept. (2003)
- Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line. Ankö, M.L., Panula, P. J. Neurochem. (2006)
- A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis. Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, T., Pedersen, O., Laakso, M., Arner, P. Am. J. Hum. Genet. (2007)
- Neuropeptide AF and FF modulation of adipocyte metabolism. Primary insights from functional genomics and effects on beta-adrenergic responsiveness. Lefrere, I., De Coppet, P., Camelin, J.C., Le Lay, S., Mercier, N., Elshourbagy, N., Bril, A., Berrebi-Bertrand, I., Feve, B., Krief, S. J. Biol. Chem. (2002)
- Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells. Mollereau, C., Mazarguil, H., Zajac, J.M., Roumy, M. Mol. Pharmacol. (2005)
- The high throughput screening of neuropeptide FF2 receptor ligands from Korean herbal plant extracts. Do, E.U., Piao, L.Z., Choi, G., Choi, Y.B., Kang, T.M., Shin, J., Chang, Y.J., Nam, H.Y., Kim, H.J., Kim, S.I. Peptides (2006)
- Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. Parker, R.M., Copeland, N.G., Eyre, H.J., Liu, M., Gilbert, D.J., Crawford, J., Couzens, M., Sutherland, G.R., Jenkins, N.A., Herzog, H. Brain Res. Mol. Brain Res. (2000)
- Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Yang, H.Y., Iadarola, M.J. Peptides (2006)
- Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta. Cikos, S., Gregor, P., Koppel, J. Biochem. Biophys. Res. Commun. (1999)
- Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors. Engström, M., Wurster, S., Savola, J.M., Panula, P. Peptides (2003)
- Structure-activity relationships of neuropeptide FF: role of C-terminal regions. Mazarguil, H., Gouardères, C., Tafani, J.A., Marcus, D., Kotani, M., Mollereau, C., Roumy, M., Zajac, J.M. Peptides (2001)