Gene Review:
Hipk2 - homeodomain interacting protein kinase 2
Mus musculus
Synonyms:
1110014O20Rik, B230339E18Rik, Homeodomain-interacting protein kinase 2, Nbak1, Nuclear body-associated kinase 1, ...
- Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. D'Orazi, G., Cecchinelli, B., Bruno, T., Manni, I., Higashimoto, Y., Saito, S., Gostissa, M., Coen, S., Marchetti, A., Del Sal, G., Piaggio, G., Fanciulli, M., Appella, E., Soddu, S. Nat. Cell Biol. (2002)
- Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival. Wiggins, A.K., Wei, G., Doxakis, E., Wong, C., Tang, A.A., Zang, K., Luo, E.J., Neve, R.L., Reichardt, L.F., Huang, E.J. J. Cell Biol. (2004)
- Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Isono, K., Nemoto, K., Li, Y., Takada, Y., Suzuki, R., Katsuki, M., Nakagawara, A., Koseki, H. Mol. Cell. Biol. (2006)
- Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis. Cecchinelli, B., Lavra, L., Rinaldo, C., Iacovelli, S., Gurtner, A., Gasbarri, A., Ulivieri, A., Del Prete, F., Trovato, M., Piaggio, G., Bartolazzi, A., Soddu, S., Sciacchitano, S. Mol. Cell. Biol. (2006)
- Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2. Kim, E.A., Noh, Y.T., Ryu, M.J., Kim, H.T., Lee, S.E., Kim, C.H., Lee, C., Kim, Y.H., Choi, C.Y. J. Biol. Chem. (2006)
- Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons. Doxakis, E., Huang, E.J., Davies, A.M. Curr. Biol. (2004)
- Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification. Hofmann, T.G., Jaffray, E., Stollberg, N., Hay, R.T., Will, H. J. Biol. Chem. (2005)
- Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo. Kim, E.J., Park, J.S., Um, S.J. J. Biol. Chem. (2002)
- Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34. Hofmann, T.G., Mincheva, A., Lichter, P., Dröge, W., Schmitz, M.L. Biochimie (2000)
- Molecular cloning of the cDNA of canine homeodomain-interacting protein kinase 2. Lee, S.Y., Chung, J.Y., Shin, I.S., Choi, E.W., Hwang, C.Y., Youn, H.Y., Han, H.R. J. Vet. Sci. (2005)