Gene Review:
UNC13A - unc-13 homolog A (C. elegans)
Homo sapiens
Synonyms:
KIAA1032, Munc13-1, Protein unc-13 homolog A
- Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2. Andrews-Zwilling, Y.S., Kawabe, H., Reim, K., Varoqueaux, F., Brose, N. J. Biol. Chem. (2006)
- Identification of the minimal protein domain required for priming activity of Munc13-1. Stevens, D.R., Wu, Z.X., Matti, U., Junge, H.J., Schirra, C., Becherer, U., Wojcik, S.M., Brose, N., Rettig, J. Curr. Biol. (2005)
- ELKS, a protein structurally related to the active zone protein CAST, is involved in Ca2+-dependent exocytosis from PC12 cells. Inoue, E., Deguchi-Tawarada, M., Takao-Rikitsu, E., Inoue, M., Kitajima, I., Ohtsuka, T., Takai, Y. Genes Cells (2006)
- Characterization of the Munc13-calmodulin interaction by photoaffinity labeling. Dimova, K., Kawabe, H., Betz, A., Brose, N., Jahn, O. Biochim. Biophys. Acta (2006)
- N type Ca2+ channels and RIM scaffold protein covary at the presynaptic transmitter release face but are components of independent protein complexes. Khanna, R., Li, Q., Sun, L., Collins, T.J., Stanley, E.F. Neuroscience (2006)
- Structural Basis for a Munc13-1 Homodimer to Munc13-1/RIM Heterodimer Switch. Lu, J., Machius, M., Dulubova, I., Dai, H., S??dhof, T.C., Tomchick, D.R., Rizo, J. PLoS Biol. (2006)
- Tumor promoter binding of the protein kinase C C1 homology domain peptides of RasGRPs, chimaerins, and Unc13s. Irie, K., Masuda, A., Shindo, M., Nakagawa, Y., Ohigashi, H. Bioorg. Med. Chem. (2004)
- Potentiation of exocytosis by phospholipase C-coupled G-protein-coupled receptors requires the priming protein Munc13-1. Bauer, C.S., Woolley, R.J., Teschemacher, A.G., Seward, E.P. J. Neurosci. (2007)
- The active zone protein CAST directly associates with Ligand-of-Numb protein X. Higa, S., Tokoro, T., Inoue, E., Kitajima, I., Ohtsuka, T. Biochem. Biophys. Res. Commun. (2007)
- Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets. Shirakawa, R., Higashi, T., Tabuchi, A., Yoshioka, A., Nishioka, H., Fukuda, M., Kita, T., Horiuchi, H. J. Biol. Chem. (2004)