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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 266 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of ATR While NBS shares overlapping characteristics with ataxia telangiectasia, it also has features overlapping with ATR- Seckel( ATR: ataxia- telangiectasia and Rad3- related protein) syndrome, a subclass of Seckel syndrome mutated in ATR. We have uncovered novel phenotypes caused by MRN... / Synonyms: Serine/threonine-protein kinase ATR
Xenopus laevis
Gene: ... High impact information on Atr Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV- damaged DNA in Xenopus egg extracts. Here, we..., including the DNA damage- dependent activation of ATM/ ATR protein kinases and several DNA damage checkpoint...
Arabidopsis thaliana
Gene: ... High impact information on ATR Here we examine the function of ATM and ATR at telomeres in Arabidopsis. ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis. ATR regulates a G2- phase cell- cycle checkpoint in Arabidopsis thaliana...
Mus musculus
Gene: ... Disease relevance of Atr We have characterized the human and mouse counterpart of the Schizosaccharomyces pombe Rad3 protein, named Atr( for ataxia- telangiectasia- and rad3- related ), and the protein that is mutated in ataxia- telangiectasia, Atm. High impact information on Atr Chk1 is an essential kinase... / Synonyms: Serine/threonine-protein kinase ATR
Homo sapiens
Gene: ... in the ATR- ATRIP- dependent maintenance of the G( 2 )- M checkpoint to ionizing and UV radiation. Physical interactions of ATRIP We show that breast- ovarian cancer susceptibility 1( BRCA1) interacts directly with ATR- interacting protein( ATRIP ), an obligate partner of ATR.... / Synonyms: ATR-interacting protein
ATR1  -  Atr1p
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of ATR1 In order to analyze whether membrane transporters of the facilitator... and compared their responses to the wild type( WT). High impact information on ATR1 Here, we isolated a new gene, designated ATR1, which when present in multiple copies per cell allowed gcn4 mutant strains...
Arabidopsis thaliana
Gene: ... Disease relevance of ATR2 An N- terminally modified form of the Arabidopsis NADPH- cytochrome P450 ATR2( ATR2mod) was expressed from the tactac promoter in Escherichia coli to obtain high yields of the enzyme. Moreover, overexpression of mutant atr2D, but not wild- type ATR2, conferred pleiotropic effects...
Arabidopsis thaliana
Gene: ... Disease relevance of ATR1 Spheroplasts of E. coli expressing CYP79B1 were reconstituted with the Arabidopsis thaliana NADPH: cytochrome P450 reductase ATR1 heterologously expressed in E. coli to obtain enzymatic activity....
Pan troglodytes
Bos taurus


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