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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 214 documents. Results 1 - 10.

Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of BLM10 The BLM3 gene was cloned from a genomic library by complementing the drug hypersensitivities conferred by the codominant blm3- 1 mutation. Mutational alteration of the BLM3..., anticancer bleomycins and structurally- related phleomycins. High impact information on BLM10 A lack of Blm3... / Synonyms: BLM3; Bleomycin resistance protein BLM10; Proteasome activator BLM10
Xenopus laevis
Gene: ... Disease relevance of blm- A In contrast to FFA- 1, chromatin binding of Xenopus Bloom syndrome helicase( xBLM) only slightly increased after replication arrest or DSB formation. High impact information on blm- A The function of Xenopus Bloom' s syndrome protein homolog( xBLM) in DNA replication.... / Synonyms: blm-A; xBLM
Mus musculus
Gene: ... Disease relevance of Blm The proportional dwarfism seen in the human is consistent with the small size and developmental delay( 12- 24 hr) seen during mid- gestation in murine Blm -/- embryos. Blm... to a mutation in the RecQ protein- like- 3 helicase gene. High impact information on Blm Red blood cells... / Synonyms: mBLM
Homo sapiens
Gene: ... Disease relevance of BLM BLM -/- cells showed hypersensitivities to the genotoxic agents as well... exchanges in WRN and BLM act as low- penetrance familial breast cancer risk factors. Of the five human Rec... of cancer or premature aging: Werner syndrome, Bloom syndrome, and Rothmund- Thomson syndrome. BLM...
Drosophila melanogaster
Gene: ... Q helicase BLM. High impact information on mus309 Furthermore, cnd2- 1 was synthetic- lethal with mutations... defects as DmBlm, support the dissolution model. We report an analysis of the Drosophila BLM gene, DmBlm... the Drosophila Bloom' s syndrome helicase homolog( DmBLM) and the Ku70 gene, which is involved in NHEJ.... / Synonyms: BLM; DmBLM; DmBlm
Gallus gallus
Gene: ... Disease relevance of BLM ORF 1, which maps entirely within UL, has the capacity to code for an 82K... information on BLM The BLM (-/-) DT40 cells showed higher sensitivity to methyl methanesulfonate and elevated levels of SCE as expected. Possible association of BLM in decreasing DNA double strand breaks during DNA...
Xenopus (Silurana) tropicalis
Gene: Synonyms: xBLM
Chemical compound: ... in BLM- sensitive human A- 253 squamous carcinoma cells but was less potent than BLM A2 or TLM S10b... and mortality appeared to be related to severe lung changes similar to the hyperoxic potentiation of BLM lung... system for bleomycin( BLM) has been formulated, and the same has been evaluated in- vivo in C57BL/ 6J...
Homo sapiens
Gene: ... patients and 502 control subjects( all caucasian) but were unable to detect an association between BH... from a variety of human tissues demonstrated that human bleomycin hydrolase is expressed in all... in BLM- induced pulmonary fibrosis and BLM resistance in tumors. Preliminary expression analysis... / Synonyms: BLM hydrolase

 

 
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