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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 1617 documents. Results 1 - 10.

Homo sapiens
Gene: ... , into prostaglandins. PTGS exist in at least 2 isoforms, PTGS1( COX- 1 ), and PTGS2( COX- 2 ). PTGS1 is constitutively...- endoperoxide synthase 2( PTGS2, commonly known as COX- 2 ), an enzyme induced by proinflammatory stimuli... the antiinflammatory and antifibrogenic molecule PGE2, apparently because of a diminished induction of COX- 2 protein... / Synonyms: COX-2; COX2; hCox-2
Mus musculus
Gene: ... R and CREB- binding sites showed synergy in repressing COX- 2 promoter activity as did mutation of all three... in myeloperoxidase activity. Furthermore, treating Apc delta716 mice with a novel COX- 2 inhibitor reduced the polyp... polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2( COX- 2). Therefore, COX- 1... / Synonyms: COX-2; COX2; Cox-2
Rattus norvegicus
Gene: ... Disease relevance of Ptgs2 Therapeutic administration of a selective COX- 2 inhibitor, SC- 58125... of selective COX- 2 inhibitors opens new avenues for the use of these compounds in decompensated cirrhosis. In this study, we investigated the effects of bile acids and duodenal reflux on COX- 2 expression in cultured... / Synonyms: COX-2; Cox-2; Cox2
Homo sapiens
Gene: ... strongly with the expression of the 2 proinflammatory enzymes, NOS2 and COX2, in breast tumors( p< 0. 001; Spearman rank correlation). Polymorphisms in prostaglandin synthase 2/ cyclooxygenase 2( PTGS2/ COX2) and risk of colorectal cancer. 43. 3% of IC rats showed chronic pneumonia and fibrosis, 40% COX2 positivity... / Synonyms: COX2
cox2  -  Cox2
Candida orthopsilosis
Gene: ... High impact information on cox2 This motif has also been found in the DNA sequence upstream from f- methionine, phenylalanine, leucine, tyrosine and glycine tRNAs, cytochrome oxidase subunit 2 and ATPase...( COX2) and apocytochrome b( CYB ), have fewer changes on a percentage basis than the nuclear- encoded...
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of COX2 We have characterized the respiration- deficient cox17 mutants and found in addition to the expected cytochrome oxidase deficiency, a specific lack of Cox2p and the presence of a misassembled cytochrome oxidase in a subset of mutants. High impact information on COX2 Accumulation...
Oryctolagus cuniculus
Gene: ... Disease relevance of COX2 Overexpression of PPARdelta using an adenovirus not only drove DRE activity but also prevented RMIC death due to COX2 inhibition. The same doses of NS- 398 and celecoxib... myocardial stunning and myocardial infarction, indicating that COX- 2 activity is necessary...
Rattus norvegicus
Gene: ... protection through up- regulating the expression of intra- pulmonary NOS and down- regulating COX2... to cyclooxygenase- 2( COX- 2) inhibition of angiogenesis in a human breast cancer model. Expression of both COX2 m... demonstrates a distinctive pattern of COX2 increases in the brain over time following traumatic brain injury... / Synonyms: COX2
Lates calcarifer
Gene: ... Analytical, diagnostic and therapeutic context of COX2 The effector proteins in late preconditioning including inducible nitric oxide synthase( iNOS ), cyclooxygenase- 2( COX- 2) were evaluated by immunoblotting as candidates for possible endogenous cardioprotective agents....
Candida albicans SC5314
Gene: ... High impact information on COX2 Compounds 1- 2( IC( 50) 2. 11- 4. 95 microg/ ml) exhibited potent but non- selective activity against the enzymes cyclooxygenase- 1( COX- 1) and cyclooxygenase- 2( COX- 2) whereas 3( IC( 50) 1. 88 microg/ ml) preferentially inhibited the enzyme COX- 2. Other interactions of COX...

 

 
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