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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 88 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of FOXO1 In addition, FOXO1A was transcriptionally down- regulated in some prostate cancers. Human endometrial fibroblasts( HuF) expressed FOXO1A, progesterone receptor A( PGRA..., expressed only FOXO1A and no detectable PGR proteins. Furthermore, expression of the FOXO1 protein is lost... / Synonyms: FOXO1A
Mus musculus
Gene: ... Disease relevance of Foxo1 In contrast, a transcriptionally inactive mutant Foxo1 partially rescues... to alanine in the nuclear export signal of Foxo1( mouse FOXO1 ), so that it would remain in the nucleus of H4... transcription stimulated by the Foxo1 mutant. We propose that low expression of SIRT1 and Foxo1 leads... / Synonyms: Foxo1a
Rattus norvegicus
Gene: ... High impact information on Foxo1a Cellular models for the analysis of signaling by protein kinase B and the forkhead transcription factor FKHR( Foxo1a).... / Synonyms: Foxo1a
Homo sapiens
Gene: ... High impact information on FOXO1B The three genes( HGMW- approved symbols FKHRP1, FKHRL1, and FKHRL1P1) map to chromosomal regions 5q35. 2- q35. 3, 6q21, and 17p11, respectively. Biological context of FOXO1B FKHRP1 and FKHRL1P1 lack introns and contain stop codons that prevent them from yielding full...
MeSH term: ... . Conversely, a gain- of- function Foxo1 mutation targeted to liver and pancreatic beta- cells results... These data indicate that Foxo1 is a negative regulator of insulin sensitivity in liver, adipocytes...- cell differentiation and metabolism. The forkhead transcription factor Foxo1 links insulin signaling...
MeSH term: ... leads to a lean and insulin sensitive phenotype. We show that haploinsufficiency of the Foxo1 gene...
Mus musculus
Gene: Synonyms: Foxo1 CoRepressor; Foxo1-corepressor
Xenopus (Silurana) tropicalis
Gene: Synonyms: foxo1a
Danio rerio
Gene: Synonyms: foxo1
Danio rerio


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