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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 122 documents. Results 1 - 10.

Mus musculus
Gene: ... of striatal neurons and chorea. Proteolytic processing of mutant Htt and abnormal calcium signaling may play a critical role in disease progression and pathogenesis. Mice expressing full- length mutant Htt, but not full- length normal Htt, displayed a progressive behavioral phenotype, consisting of slowed... / Synonyms: htt
Homo sapiens
Gene: ... tract in the protein huntingtin( Htt ), which leads to its aggregation in nuclear and cytoplasmic... is to identify signaling cascades initiated by mutant Htt that lead to neuronal cell death and dysfunction... and degradation can be selectively enhanced by polyQ- expanded htt. The serum- and glucocorticoid- induced kinase...
Drosophila melanogaster
Gene: ... Disease relevance of htt In cell and tissue culture models of HD, anti- N- terminal huntingtin... that results in intracellular aggregate formation and neurodegeneration. High impact information on htt.... Huntington disease is caused by the expansion of a polyglutamine repeat in the Huntingtin protein( Htt... / Synonyms: DmHtt; HTT; Htt
Rattus norvegicus
Gene: ... in virtually all striatal neurons including SS/ NPY/ NADPH- d neurons. Neural progenitor transplantation... ameliorated toxicity caused by either mutant Htt or 3- NP. Huntington' s disease( HD) is an autosomal dominant.... Psychiatry related information on Hdh Interactions between mutant huntingtin( Htt) and a variety...
Homo sapiens
Gene: Synonyms: HTT-AS1
Homo sapiens
Gene: ... ), which is expressed in brain and blood cells. The serotonin transporter( 5- HTT) mRNA is found in all... and schizophrenia susceptibility, we performed a meta- analysis based on all original published association studies... in schizophrenia and 5- HT transporters( 5- HTT) in depression and bulimia. OBJECTIVES: To clarify whether SERT... / Synonyms: 5-HTT; 5HTT; HTT
Danio rerio
Gene: ... High impact information on hd Expression of mutant htt increased the frequency of embryos with abnormal morphology and the occurrence of apoptosis....
Xenopus (Silurana) tropicalis
Gene: ... High impact information on hd RESULTS: The C. intestinalis htt transcript exhibits some peculiar... vertebrate and ascidian lineages predominantly in the 5 '- half of the htt gene, where there is also evidence of lineage- specific evolutionary dynamics in vertebrates. The exon- intron organization of the htt gene...
Mus musculus
Gene: ... , all measures were normal with the exception that 5- HTT -/- mice on the C57BL/ 6J background showed...- HTT gene may cause osteopenia. Previous studies demonstrated that the serotonin( 5- hydroxytryptamine; 5- HT) transporter( 5- HTT) mediates the mitogenic activity of 5- HT in pulmonary vascular SMCs... / Synonyms: 5-HTT; 5HTT; Htt
Macaca mulatta
Gene

 

 
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