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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 87 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of IRF3 In cells transiently expressing IRF7 or/ and IRF3, the VAF level... particle entry requires IRF3 but not virus replication. Furthermore, we demonstrate that HSV- 1 modifies the IRF3 pathway in a manner different from that of the small RNA viruses most commonly studied... / Synonyms: IRF-3
Mus musculus
Gene: ... Disease relevance of Irf3 The data suggest that pre- activated IRF- 3 is a major factor... that polyubiquitination of IRF- 3 increases in response to Sendai virus infection. Local delivery of murine recombinant IFN- beta protected C57BL/ 6 and IRF- 3 (-/-) mice against IVAG HSV- 2 challenge. The host response... / Synonyms: IRF-3
Bos taurus
Gene: ... Disease relevance of IRF3 Rotavirus non- structural protein NSP1 binds to and targets IRF3... protease N( pro) of BVDV appears to be, at least partly, responsible for suppressing IRF- 3 activation... involves a block to IRF- 3 function, and we speculate that this may be a key characteristic...
MeSH term: ... In unstimulated cells, IRF- 3 is present in an inactive cytoplasmic form; following Sendai virus infection, IRF- 3... and immunoblotting with a novel phosphospecific antibody, we show for the first time that, in vivo, IRF- 3... gene I( RIG- I ), a putative cellular RNA helicase. In cells transiently expressing IRF7 or/ and IRF3...
MeSH term: ... axis by membrane- bound TGF- beta. Competition with GR for GRIP1 antagonizes IRF3- mediated transcription, identifying the GRIP1: IRF3 interaction as a novel target for glucocorticoid immunosuppression...
Homo sapiens
Gene: ... and endothelial cells. Other interactions of TLR3 IRF3 mediates a TLR3/ TLR4- specific antiviral gene program. We demonstrate that, when the TLR3 pathway is stimulated, the levels of phosphorylated IRF3 are reduced... and illustrating that W protein- mediated inhibition is due to a loss of active IRF3. In contrast, enhanced CXCL11...
Homo sapiens
Gene: ... . IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. These include the kinase TBK1... and other DNA- associated immune disorders. We conclude that TBK1 is essential for IRF3- dependent antiviral... genomics: TBK1 and the IRF3 pathway. The protein kinase TBK1 is a key regulator inducing phosphorylation...
Macaca mulatta
Gene
Pan troglodytes
Gene
Canis lupus familiaris
Gene

 

 
Links to contributing authors: Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
 
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