Your search matched a total of 228 documents. Results 1 - 10.
Homo sapiens
Gene: ... Disease relevance of NPC1L1 Combination therapy using a novel, specific, and potent cholesterol absorption( NPC1L1) inhibitor( ezetimibe) and HMG- CoA reductase inhibitors( statins) offers an efficacious... line stably expressing human NPC1L1 was established, and cholesterol uptake was studied. Furthermore...
Mus musculus
Gene: ... genotypes, the Npc1 mRNA was detected in the majority of neurons in nearly all regions, but at significantly...Disease relevance of Npc1 By 7 weeks of age, the sterol pool in the NPC mice had increased from 2... were also evaluated in Npc1 (-/-) mice, and the beneficial effects were found to be greater than...
Homo sapiens
Gene: ... Disease relevance of NPC1 Combined with results from time- lapse microscopy and in vivo brain injections, our findings suggest that this adenovirus offers advantages for expressing NPC1 and analyzing its... immunoreactivity in liver and spleen tissue from patients with Niemann- Pick disease type C1( NPC1). The goal...
Mus musculus
Gene: ... Disease relevance of Npc1l1 Male Npc1l1 -/- and Npc1l1/ apoE -/- mice were completely resistant... in hepatic and biliary cholesterol levels. High impact information on Npc1l1 Moreover, GW610742 treatment... with a significantly reduced expression of the cholesterol absorption protein Niemann- Pick C1- like 1( Npc1l1...
Drosophila melanogaster
Gene: ... Disease relevance of NPC1 Niemann- Pick type C( NPC) disease is a fatal autosomal- recessive... information on NPC1 A Drosophila model of the Niemann- Pick type C lysosome storage disease: dnpc1a..., regulated by Ptc1, and late endosomal lipid sorting, regulated by the Ptc- related Niemann- Pick C1( NPC1... / Synonyms: NPC1; NPC1a; Npc1
Sus scrofa
Gene: ... High impact information on NPC1 The Niemann Pick- C1( NPC- 1) protein is essential... the catalytic subunit of PKA was overexpressed in Y- 1 cells, there were similar increases in NPC- 1 promoter activity in the presence of CREB. NPC- 1 promoter activity was induced by treatment with dibutryl cAMP( dbc...
Homo sapiens
Gene: ... Disease relevance of NPC1 Niemann- Pick type C1( NPC1) disease is a fatal neurodegenerative disease..., these results demonstrate that there are multiple defects in sperms from mice lacking a functional NPC1 protein... of the Sphingomonas Ag trafficked to the lysosome of wild- type cells but accumulated in the late endosome of NPC1...
Felis catus
Gene: ... Disease relevance of NPC1 The diseases studied include GM1- and GM2- gangliosidosis..., and an undefined glycolipid storage disease. High impact information on NPC1 Niemann- Pick C( NPC) disease... transport of cholesterol. The current study was conducted to characterize the Niemann- Pick C1( NPC1...
MeSH term: ... , a glycoprotein of 84, 000 daltons could be purified which has all the properties expected from the Fab target and accounts for most of the Fab- inhibiting activity of embryonal carcinoma cell membranes. Expression of NPC1... the lipid bilayer of cell membranes, all cells require a mechanism for sulfate influx and efflux to ensure...
Links to contributing authors:
Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
