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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 90 documents. Results 1 - 10.

Rattus norvegicus
Gene: ... Disease relevance of Ogt Escherichia coli strains that are deficient in the Ada and Ogt DNA repair... by endogenous metabolites. High impact information on Ogt We demonstrate that, in close parallel with mutagenesis, the Ogt ATase sensitizes the bacteria to the lethal effects of these carcinogens, suggesting... / Synonyms: OGT
Mus musculus
Gene: ... High impact information on Ogt We further segregated the mutant Ogt allele to parental gametes by oocyte- and spermatid- specific Cre- loxP mutagenesis. Ogt- dependent X- chromosome- linked protein glycosylation is a requisite modification in somatic cell function and embryo viability. The Ogt gene encodes... / Synonyms: OGT
Caenorhabditis elegans
Gene: ... Disease relevance of ogt- 1 Based on its substrate specificity and molecular features, we propose... in the pathogenesis of diabetes mellitus. The O- GlcNAc transferase( OGT) catalyzing O- GlcNAc addition is essential... may be deregulated in diabetes and neurodegenerative disease. High impact information on ogt- 1...
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Gene: ... Disease relevance of ogt Compared with Salmonella typhimurium TA1535, mutagenic activity was enhanced in ogt gene- deficient strains( YG7108 and YG7104 ), suggesting that an O( 6 )- alkylguanine adduct causes the mutation. High impact information on ogt The parental S. typhimurium YG7108, derived...
Escherichia coli str. K-12 substr. MG1655
Gene: ... Disease relevance of ogt Characterisation and nucleotide sequence of ogt, the O6- alkylguanine- DNA...- alkyltransferase gene ogt reduces the toxicity of alkylnitrosoureas. These results indicate that ogt gene... that suggests a novel role for RpoS in DNA repair functions. High impact information on ogt The human cDNA has...
Homo sapiens
Gene: ... Disease relevance of OGT To facilitate mutational analysis of OGT in the absence of competing endogenous activity, we expressed the 103- kDa human OGT in Escherichia coli. Thus, we propose that OGT can... the diabetogenic agent alloxan( ALX ), also a UDP- GlcNAc analog irreversibly inhibits OGT. As our data suggest...
Drosophila melanogaster
Gene: ... High impact information on Ogt Similar to E. coli Ogt and yeast alkyltransferase but in contrast to the human alkyltransferase, the Drosophila alkyltransferase is resistant to inactivation by O 6- benzylguanine.... / Synonyms: OGT; Ogt; sxc/Ogt
Caenorhabditis remanei
Gene
Caenorhabditis briggsae
Gene
Danio rerio
Gene: Synonyms: ogt

 

 
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