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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 89 documents. Results 1 - 10.

Homo sapiens
Gene: ... and all cell lines, unlike PBX1, which is not expressed in lymphoid cell lines. The prognostically... precursor acute lymphoblastic leukemia( ALL ), leading to formation of a fusion gene( E2A- PBX1... cooperation with PBX1. Molecular studies showed E2A- PBX1 abnormalities in all examined cases( 12 of 12... / Synonyms: Homeobox protein PBX1
Mus musculus
Gene: ... Disease relevance of Pbx1 It has been proposed that some of the oncogenic potential of E2A- Pbx1... and mouse leukemias. In pre B cell leukemias containing the t( 1; 19) chromosome translocation, Pbx1...2A. E2a- Pbx1 is an oncogenic derrivative of Pbx1 produced by the t( 1; 19) translocation... / Synonyms: Homeobox protein PBX1; Pbx-1; Pbx1a
Xenopus laevis
Gene: ... High impact information on pbx1b Pbx1 is a homeodomain protein that functions in complexes with other homeodomain- containing proteins to regulate gene expression during embryogenesis and oncogenesis.... / Synonyms: pbx1b
Xenopus (Silurana) tropicalis
Gene: Synonyms: pbx1b
MeSH term: ... - PBX1 also markedly altered lymphoid development in pretumorous animals, reducing the number...
MeSH term: ... . Analysis with molecular markers revealed the effective induction of tubulogenic mesenchyme; however, Pbx1... capacity for compensatory growth in all nephron segments and even in portions of tubular segments... transformation of virtually all nephrons and collecting ducts( serum urea: 616 +/- 195 mg/ dl; kidney- to- body...
Danio rerio
Gene: Synonyms: pbx1b
MeSH term: ... to inhibition of apoptosis, hyperplasia, and tumor formation. Chimeric homeobox gene E2A- PBX1 induces..., and programmed cell death. All apoptosis signaling pathways converge on a common machinery of cell destruction...
MeSH term: ... by clefts or constrictions. Taken together, these data indicate that Pbx1 is essential for the function... of the constriction region, in particular histidine 182, which is conserved among all known water- specific channels...
Mus musculus
Gene: ... . A hybrid POU/ Pbx binding site is recognized in vitro by Pbx- 1, Brn- 1 and Brn- 2. Two of the four DNA...


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